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Figure 1: Compartmental models describing the receptor kinetics of [123I] IACFT in human brain. A 3 compartment model (upper) was used to analyze the striatal time-activity data and a 2 compartment model (lower) was used to fit the occipital cortical data.
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Figure 2: Representative time-activity curves for: striatum (average), occipital cortex, frontal cortex and cerebellum expressed as nCi/ml.
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Figure 3: Trans-axial, sagittal and coronal SPECT images of the brain of a normal subject at 30 to 45 min. after injection of 10 mCi of [123I] IACFT.
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Figure 4: Time dependence of total plasma radioactivity and intact [123I]-IACFT.
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Figure 5: Representative Logan plots for striatum and occipital cortex derived from SPECT data acquired after injection of 10 mCi of [123I] IACFT.
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Figure 6: Plot of (StrTAC - OccTAC) and the corresponding gamma variate fit for one of the subjects.
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