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Table 2. Radioligand Binding Densities Determined by Quantitative Receptor Autoradiography in adjacent tissue sections of Squirrel Monkey (Saimiri sciureus) Brain.


YM 09151-2YM 09151-2
(sulpiride insensitive)
WIN 35,428SCH 23390
Region
MPFC++++++
MS++++++
Cd+++++-+++++++++++
Put+++++-+++++++++++
NaOT++++-++++++++++
ST++-++++++
GPi+-++++
GPe++-+++
VP++-+++++
Hypo+++++
PV---++
Cl++++++
Amy++++++++
Thal+-++
Hipp+-+++
HippL+++++++
Sn/VTA++-++++++
Ctx+++++

Specific binding was determined in autoradiographs of tissue incubated with [3H]WIN 35,428 (5 nM), [3H]SCH 23390 (0.5 nM) and [3H]YM 09151-2 (0.2 nM). Brain Region Abbreviations are found in the legend to Figure 4.


Binding densities (pmol/g) in squirrel monkey brain:
++++++> 120
+++++85 - 119
++++50 - 84
+++25 - 49
++10 - 24
+1 - 9
-Background

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