Figure 4: Ethanol produces a concentration dependent stimulation of alpha1and alpha2 receptors. Oocytes were bath perfused with approximately equieffective concentrations (EC4) of glycine, 15uM (alpha1) and 50 uM (alpha2) for 30 sec. Oocytes were perfused with ethanol (50-200 mM) for 1 min prior to exposure to glycine plus ethanol. Values are expressed as a percent above the respective control glycine response (n=4-11).