
Figure 6: Butanol produced a concentration dependent stimulation of alpha1 and
alpha2 receptors. Oocytes were perfused with approximately equieffective concentrations (EC4)
of glycine, 15uM (alpha1) and 50 uM (alpha2) for 30 sec. Oocytes were perfused with butanol
(2.5-40 mM) for 1 min prior to exposure to glycine plus butanol. Values are expressed as a
percent potentiation above the respective control glycine response (n=4-9).