Figure 7: Butanol increases the potency, but not the efficacy of glycine receptors. Oocytes (alpha1: upper panel, alpha2: lower panel) were perfused with glycine (15-500 uM) for 30 sec. Oocytes were perfused with butanol (10mM) for 1 min prior to application of glycine plus butanol for 30 sec. Values are expressed as a percent potentiation above the respective control glycine response (n=5-8).